Little Miss Trouble

In series

Mr. Mischief: Both are yellow and are pranksters.
Little Miss Naughty: Both are pranksters.
Little Miss Bad: Both are pranksters, and have the same shape and hairstyles.
Little Miss All-Goes-Well: Both seem to be between yellow and brown body colours.
Little Miss Busy-Body: Both are yellow and annoy people.
Little Miss Giggles: Both have the same body shape, have red hair with pigtails, freckles, and like to laugh.
Mr. Crosspatch: Both have red and cause trouble.
Little Miss Scary: Both cause trouble.
Mr. Tickle: Both are round and annoy people sometimes.
Mr. Chatterbox & Little Miss Chatterbox: All 3 of them annoy people sometimes.
Mr. Cheeky: Both are pranksters.

Bart Simpson (The Simpsons, both of them are yellow, wear blue, and troublemakers),
Harley Quinn (Batman, DC Comics, both cause trouble, laugh, annoy people and are boyfriends to Mr. Mischief and The Joker),
Peppermint Fizz (Strawberry Shortcake, both like to get in trouble),
Raisin Cane (Strawberry Shortcake, both are troublemakers),
Troublesome Trucks (The Railway Series, all are naughty),
Chewoo (Yoohoo And Friends, both are troublemakers),
Sly and Gobbo (Noddy, all three are naughty and troublesome),
Bowser Jr. (Super Mario Bros. both are yellow and cause trouble),
Kairi (Kingdom Hearts, both have red hair),
Ninki (Kerwhizz, both have yellow and are naughty),
Rainbow Dash (My Little Pony, both can be troublesome)
Mosquito (Tinga Tinga Tales, both love to spread rumours and cause trouble)
Black Spy (Spy vs Spy; both are naughty and sometimes like trouble)
Fifi La Fume (Tiny Toon Adventures, both can be troublesome)
Tell-Tale Tallulah (Little Monsters, both spread rumours)
Reggie Mantle (Archie series, both are troublesome)
Angelica Pickles (Rugrats, both are troublesome)
Brother Blood (Teen Titans, both can tend to cause trouble)
Four (Seven Little Monsters, both wear yellow and cause trouble sometimes)
Jessica Lovejoy (The Simpsons, both are yellow, wear a bow somewhere in their hair, and are troublemakers)
Veronica Lodge (Archie series, both wear yellow and red and are troublesome sometimes)
Bill and Ben (The Railway Series, all three are yellow and troublemakers)